Thick ascending branch of the loop of Henle. Castle MB. The thick ascending limbs of Henle‘s loop have at least three main roles: (1) They reabsorb sodium chloride, which dilutes the urine.
What else happens in the thick ascending limb?
Thick ascending leg
Sodium (Na+), potassium (K+) and chloride (Cl−) ions are resorbed through active transport. This promotes greater paracellular reabsorption of Na+as well as other cations such as magnesium (Mg2+) and especially calcium Ca2+due to charge repulsion.
Also, is the thick ascending leg permeable to water?
The thin descending leg has low ionic and urea permeability, with high water permeability at the same time. The loop has a sharp bend in the renal medulla, going from the descending to the ascending thin limb. The thin ascending limb is impermeable to water but permeable to ions.
Similarly, you may be wondering what the main function of the loop of Henle is?
The principle function of the loop of Henle appears to be recovery of water and sodium chloride from the urine. This function allows for the production of urine that is much more concentrated than blood, limiting the amount of water needed for survival.
What happens to sodium and chloride in the ascending part of the nephron loop?
The ascending limb (where loop diuretics act) is impermeable to water. NaCl is pumped from the tubule into the interstitium in the ascending limb. Tubular osmolarity decreases and the fluid exiting the loop is hypotonic. The collecting duct is impermeable to water without ADH.
What is absorbed in the collecting duct?
The main task of the collecting duct is the absorption of water through the action of anti-diuretic hormone (ADH) and aquaporins. This hormone acts on the renal tubules to increase the number of aquaporin-2 channels (water channels) in the apical membrane of the tubular cells in the collecting duct.
What is the largest component of urine by weight other than water?
What does the vasa recta?
Function of the vasa recta. The vasa recta, the capillary networks that that supply blood to the marrow are highly permeable to solutes and water. As in the loop of Henle, the vasa recta form a parallel set of hairpin loops within the medulla (see Chapter 2).
Where is water reabsorbed in the nephron?
The first part of the nephron , which is responsible for water absorption is the proximal convoluted tubule. Filtered fluid enters the proximal tubule from Bowman’s capsule. Many substances that the body needs and that may have been filtered out of the blood at the glomerulus are reabsorbed into the body in this segment.
What is the function of the glomerulus?
In the kidney, a tiny spherical structure made up of capillary blood vessels that are actively involved in filtering the blood to form urine. The glomerulus is one of the key structures that make up the nephron, the functional unit of the kidney.
Why is the ascending limb impermeable to water?
The thin ascending limb is impermeable to water, but permeable to ions. Due to the high concentration of ions in the filtrate and the low concentration in the tissue fluid, they passively diffuse out of the thin ascending limb.
What is the collecting channel permeable to?
The collecting tube system is under the control of the antidiuretic hormone (ADH). In the presence of ADH, the collecting duct becomes permeable to water. The high osmotic pressure in the medulla (created by the countercurrent multiplier system/loop of Henle) then pulls water from the renal tubule back into the vasa recta.
How does the loop of Henle help conserve water?
Kidney retention of water. The kidney conserves water by first diluting the urine as it moves through the loop of Henle, and then concentrating the urine in the distal tubules and collecting ducts (the latter under the influence of the antidiuretic hormone, or ADH).
Where is the loop of Henle located?
Answer and explanation: The loop of Henle is located in the renal medulla, it is the next level in the renal tubular process after the proximal tubule.
Where is the collecting duct located?
Collecting ducts descend through the cortex and medulla and successively fuse near the inner medullary region. Towards the tip of the papillary, converging papillary ducts form about 20 large ducts that open into the renal pelvis. The collecting ducts are composed of two cell types: principal and intercalated cells.
What does the distal tubule do?
Once the filtrate passes the thick ascending limb of Henle, it enters the distal convoluted one Tubule, a channel of the renal tubule in the renal cortex that reabsorbs calcium, sodium and chloride and regulates urine pH by secreting protons and absorbing bicarbonate.
Where urine is formed ?
Where is urine most concentrated in the kidney?
The renal medulla produces concentrated urine through the creation of an osmotic gradient that extends from the corticomedullary region to the border inner medulla.
What happens in the collecting duct?
The last part of a long, winding tube that carries urine from the nephrons (cell structures in the kidney that filter blood and make urine) and transport to the renal pelvis and ureters. Also called renal collecting duct.
What is the function of the ascending loop of Henle?
The thick ascending limb of the loop of nephron connects to the distal convoluted tubule, which connects to the urinary connecting duct. The loop of Henle is immersed in the marrow, which is very salty due to the uptake of ions. Sodium is constantly pumped out of the ascending limb into the marrow.
What is the function of the collection tube?
Renal collecting duct, also called Bellini duct, one of the long narrow tubes in the kidney that concentrates urine from the nephrons, the main functional units of the kidneys, and transports it to larger ducts that connect to the nephrons are calyces, cavities in which urine collects until it flows through the kidneys
What is the functional unit of the kidney?
What is the nephron, the functional unit of the kidney, responsible for Remove waste from the body. Each kidney is made up of over a million nephrons, which dot the renal cortex, giving it a granular appearance when sectioned sagittal (front to back).